{{Rsnum
|rsid=10999845
|Gene=CDH23
|Chromosome=10
|position=73240361
|Orientation=plus
|GMAF=0.1818
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 62.8 | 35.4 | 1.8
| HCB | 71.5 | 24.1 | 4.4
| JPT | 59.3 | 38.9 | 1.8
| YRI | 78.9 | 19.7 | 1.4
| ASW | 71.9 | 26.3 | 1.8
| CHB | 71.5 | 24.1 | 4.4
| CHD | 65.1 | 31.2 | 3.7
| GIH | 87.1 | 12.9 | 0.0
| LWK | 80.0 | 19.1 | 0.9
| MEX | 58.6 | 37.9 | 3.4
| MKK | 76.9 | 19.9 | 3.2
| TSI | 65.7 | 32.4 | 2.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs10999845
|Name_s=
|Gene_s=CDH23
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Smoking Initiation (p = 0.00005807; OR for minor allele G:1.32)
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164920597
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs10999845
|overall_frequency_n=18
|overall_frequency_d=120
|overall_frequency=0.15
|n_genomes=15
|n_genomes_annotated=0
|n_haplomes=17
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}