{{Rsnum
|rsid=11052552
|Chromosome=12
|position=9703362
|Orientation=plus
|GMAF=0.4596
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene=CLECL1
|Gene_s=CLECL1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 31.9 | 46.0 | 22.1
| HCB | 43.8 | 46.7 | 9.5
| JPT | 38.1 | 50.4 | 11.5
| YRI | 2.7 | 30.6 | 66.7
| ASW | 0.0 | 47.4 | 52.6
| CHB | 43.8 | 46.7 | 9.5
| CHD | 39.4 | 49.5 | 11.0
| GIH | 26.3 | 49.5 | 24.2
| LWK | 0.0 | 14.7 | 85.3
| MEX | 29.3 | 51.7 | 19.0
| MKK | 0.6 | 21.8 | 77.6
| TSI | 20.6 | 46.1 | 33.3
| HapMapRevision=28
}}[[rs11052552]] has been reported in a large study to be associated with [[type-1 diabetes]].

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.49 (CI 1.28-1.73), and for homozygotes, 1.43 (CI 1.21-1.69). {{PMID|17554300|OA=1
}}

{{GWAS Summary
|SNP=rs11052552
|PubMedID=17554300
|Condition=Type 1 diabetes
|Gene=NR
|Risk Allele=G
|pValue=7.00E-007
|OR=1.49
|95CI=1.28-1.73
|OA=1
}}

{{PharmGKB
|RSID=rs11052552
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,963 cases, 2,938 controls; Replication Sample Size: (see Todd 2007); Risk Allele: rs11052552-G). This variant is associated with type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356637
}}

{{PMID Auto
|PMID=22496761
|Title=Improving Power of Genome-Wide Association Studies with Weighted False Discovery Rate Control and Prioritized Subset Analysis
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11052552
|overall_frequency_n=45
|overall_frequency_d=118
|overall_frequency=0.381356
|n_genomes=30
|n_genomes_annotated=0
|n_haplomes=41
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}