{{Rsnum
|rsid=1109374
|Gene=AK4
|Chromosome=1
|position=65167814
|Orientation=plus
|GMAF=0.3567
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=AK4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 4.5 | 28.2 | 67.3
| HCB | 31.6 | 48.1 | 20.3
| JPT | 27.5 | 55.0 | 17.4
| YRI | 15.5 | 51.4 | 33.1
| ASW | 10.5 | 56.1 | 33.3
| CHB | 31.6 | 48.1 | 20.3
| CHD | 32.7 | 47.1 | 20.2
| GIH | 5.1 | 20.2 | 74.7
| LWK | 13.0 | 50.9 | 36.1
| MEX | 1.8 | 31.6 | 66.7
| MKK | 5.8 | 36.1 | 58.1
| TSI | 5.9 | 31.4 | 62.7
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs1109374
|Name_s=
|Gene_s=AK3L1, AK3L2
|Feature=
|Evidence=PubMed ID:19268276
|Annotation=In a GWAS of 3497 Dutch subjects from the Netherlands Study of Depression and Anxiety or from the Netherlands Twin Registry, this SNP was found to be associated with Current Smoking (p = 0.00007972;OR for minor allele C:1.276).
|Drugs=nicotine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA164924494
}}

{{PMID Auto
|PMID=18519066
|Title=Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1109374
|overall_frequency_n=29
|overall_frequency_d=122
|overall_frequency=0.237705
|n_genomes=23
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}