{{Rsnum
|rsid=11099592
|Gene=HPSE
|Chromosome=4
|position=83309466
|Orientation=plus
|GMAF=0.1919
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=HPSE
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 60.4 | 36.0 | 3.6
| HCB | 81.0 | 16.8 | 2.2
| JPT | 69.0 | 27.4 | 3.5
| YRI | 81.0 | 17.7 | 1.4
| ASW | 84.2 | 15.8 | 0.0
| CHB | 81.0 | 16.8 | 2.2
| CHD | 79.8 | 19.3 | 0.9
| GIH | 71.3 | 24.8 | 4.0
| LWK | 68.2 | 29.1 | 2.7
| MEX | 51.7 | 41.4 | 6.9
| MKK | 65.4 | 28.2 | 6.4
| TSI | 57.8 | 39.2 | 2.9
| HapMapRevision=28
}}{{PMID Auto
|PMID=20578081
|Title=Association of heparanase gene (HPSE-1) single nucleotide polymorphisms with gastric cancer
}}

{{PMID Auto
|PMID=22276173
|Title=Polymorphisms and a haplotype in heparanase gene associations with the progression and prognosis of gastric cancer in a northern chinese population
|OA=1
}}

{{PMID Auto
|PMID=17611567
|Title=Association of heparanase gene (HPSE) single nucleotide polymorphisms with hematological malignancies.
}}

{{PMID Auto
|PMID=19406828
|Title=Inverse correlation between HPSE gene single nucleotide polymorphisms and heparanase expression: possibility of multiple levels of heparanase regulation.
|OA=1
}}

{{GET Evidence
|gene=HPSE
|aa_change=Lys307Arg
|aa_change_short=K307R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11099592
|overall_frequency_n=8549
|overall_frequency_d=10742
|overall_frequency=0.795848
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=98
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.001
|nblosum100=-3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}