{{Rsnum
|rsid=111290936
|Gene=EIF4G1
|Chromosome=3
|position=184322089
|Orientation=plus
|Summary=Late-onset Parkinson's disease 
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=EIF4G1
}}[[rs111290936]], also known as Ala502Val or A502V, is a SNP in the eukaryotic translation initiation factor 4 gamma, 1 [[EIF4G1]] gene on chromosome 3. 

A study of several cases of familial [[Parkinson's disease]] concluded that [[rs111290936]](T), a very rare allele, is likely to be a dominant mutation leading to late-onset disease. Other mutations in the [[EIF4G1]] gene were also found, with varying degrees of certainty regarding their pathogenicity.{{doi|10.1016/j.ajhg.2011.08.009}}{{ClinVar
|ALT=T
|CHROM=3
|CLNACC=RCV000022976.1
|CLNALLE=1
|CLNDBN=Parkinson disease 18
|CLNDSDB=MedGen:OMIM:Orphanet
|CLNDSDBID=C3280271:614251:2828
|CLNHGVS=NC_000003.11:g.184039877C>T
|CLNSIG=5
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=600495.0002
|Disease=Parkinson disease 18
|FwdALT=T
|FwdREF=C
|GENEINFO=EIF4G1:1981
|GENE_ID=1981
|GENE_NAME=EIF4G1
|REF=C
|RSPOS=184039877
|Reversed=0
|SAO=0
|SSR=0
|Tags=PM;OTHERKG;LSD;OM
|VC=SNV
|VP=0x050060000000000002110100
|WGT=0
|dbSNPBuildID=132
|rsid=111290936
}}