{{Rsnum
|rsid=11212617
|Gene=C11orf65
|Chromosome=11
|position=108412434
|Orientation=plus
|GMAF=0.4706
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Summary=influences Metformin response
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=C11orf65
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 26.5 | 54.0 | 19.5
| HCB | 16.1 | 39.4 | 44.5
| JPT | 19.5 | 40.7 | 39.8
| YRI | 2.0 | 32.0 | 66.0
| ASW | 17.5 | 36.8 | 45.6
| CHB | 16.1 | 39.4 | 44.5
| CHD | 16.5 | 49.5 | 33.9
| GIH | 46.5 | 38.6 | 14.9
| LWK | 3.7 | 29.6 | 66.7
| MEX | 36.2 | 41.4 | 22.4
| MKK | 8.3 | 32.7 | 59.0
| TSI | 53.9 | 33.3 | 12.7
| HapMapRevision=28
}}{{CPMC SNP
|link=https://cpmc.coriell.org/Sections/Results/Metformin.aspx
}}Influences [[Metformin]] response{{PMID Auto GWAS
|PMID=21186350
|Trait=None
|Title=Common variants neat ATM are associated with glycemic response to metformin in type 2 diabetes
|RiskAllele=C
|Pval=3E-9
|OR=1.3500
|ORtxt=[1.22-1.49]
|OA=1
}}

{{PMID Auto GWAS
|PMID=21845381
|Trait=None
|Title=Does metformin work for everyone? A genome-wide association study for metformin response.
|RiskAllele=A
|Pval=3E-9
|OR=None
|ORtxt=None
}}

{{PMID Auto
|PMID=22453232
|Title=A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.
|OA=1
}}

{{PMID Auto
|PMID=23171036
|Title=Metformin: a cheap and well-tolerated drug that provides benefits for viral infections
}}

{{PMID Auto
|PMID=22751958
|Title=The C allele of ATM rs11212617 does not associate with metformin response in the Diabetes Prevention Program.
|OA=1
}}

{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}