{{Rsnum
|rsid=11225434
|Gene=LOC100288077
|Chromosome=11
|position=102820751
|Orientation=plus
|GMAF=0.3994
|Gene_s=COX6CP3
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 31.9 | 51.3 | 16.8
| HCB | 10.9 | 40.9 | 48.2
| JPT | 8.0 | 38.9 | 53.1
| YRI | 16.3 | 53.1 | 30.6
| ASW | 19.3 | 54.4 | 26.3
| CHB | 10.9 | 40.9 | 48.2
| CHD | 13.8 | 42.2 | 44.0
| GIH | 7.9 | 34.7 | 57.4
| LWK | 9.1 | 50.0 | 40.9
| MEX | 10.3 | 46.6 | 43.1
| MKK | 14.1 | 42.3 | 43.6
| TSI | 24.5 | 48.0 | 27.5
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20031604
|Trait=Serum Matrix Metalloproteinase
|Title=Genome-Wide Association Scan Identifies Variants near Matrix Metalloproteinase (MMP) Genes on Chromosome 11q21-22 Strongly Associated With Serum MMP-1 Levels
|RiskAllele=C
|Pval=9E-29
|OR=0.39
|ORtxt=[NR] unit increase in ln(MMP-1)
|OA=1
}}

{{PharmGKB
|RSID=rs11225434
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:20031604
|Annotation=In a GWAS performed on 778 healthy Amish adults, this SNP was significantly associated with levels of circulating MMP1. Phenotype: associated with circulating MMP1 levels. Study size:778. Study population/ethnicity: healthy Amish adults. Significance metric(s): P value: GC content -corrected p = 2.07 x 10 (-19). Type of association: CO; GN.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA165111635
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11225434
|overall_frequency_n=57
|overall_frequency_d=128
|overall_frequency=0.445312
|n_genomes=40
|n_genomes_annotated=0
|n_haplomes=50
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}