{{Rsnum
|rsid=11226373
|Chromosome=11
|position=104463511
|Orientation=plus
|GMAF=0.1474
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 77.9 | 19.5 | 2.7
| HCB | 68.6 | 29.2 | 2.2
| JPT | 61.1 | 32.7 | 6.2
| YRI | 70.1 | 29.3 | 0.7
| ASW | 64.9 | 33.3 | 1.8
| CHB | 68.6 | 29.2 | 2.2
| CHD | 74.3 | 23.9 | 1.8
| GIH | 67.3 | 27.7 | 5.0
| LWK | 63.6 | 34.5 | 1.8
| MEX | 86.2 | 13.8 | 0.0
| MKK | 67.3 | 27.6 | 5.1
| TSI | 78.4 | 19.6 | 2.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20031604
|Trait=Serum Matrix Metalloproteinase
|Title=Genome-Wide Association Scan Identifies Variants near Matrix Metalloproteinase (MMP) Genes on Chromosome 11q21-22 Strongly Associated With Serum MMP-1 Levels
|RiskAllele=G
|Pval=2E-18
|OR=0.44
|ORtxt=[NR] unit increase in ln(MMP-1)
|OA=1
}}

{{PharmGKB
|RSID=rs11226373
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:20031604
|Annotation=In a GWAS performed on 778 healthy Amish adults, the C allele of rs11226373 was associated with higher levels of circulating MMP1. Risk or phenotype-associated allele: C allele. Phenotype: associated with higher circulating MMP1 levels. Study size:778. Study population/ethnicity: healthy Amish adults. Significance metric(s): P value: p less than or equal to 10 (-7). Type of association: CO; GN.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA165111633
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11226373
|overall_frequency_n=22
|overall_frequency_d=128
|overall_frequency=0.171875
|n_genomes=20
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}