{{Rsnum
|rsid=11254363
|Gene=CUBN
|Chromosome=10
|position=17130693
|Orientation=plus
|GMAF=0.2144
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 56.8 | 35.1 | 8.1
| HCB | 93.4 | 6.6 | 0.0
| JPT | 96.5 | 3.5 | 0.0
| YRI | 51.0 | 40.1 | 8.8
| ASW | 61.4 | 29.8 | 8.8
| CHB | 93.4 | 6.6 | 0.0
| CHD | 95.4 | 4.6 | 0.0
| GIH | 35.0 | 50.0 | 15.0
| LWK | 53.2 | 43.1 | 3.7
| MEX | 75.9 | 22.4 | 1.7
| MKK | 45.8 | 43.8 | 10.5
| TSI | 23.8 | 52.5 | 23.8
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19303062
|Trait=Folate pathway vitamins
|Title=Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
|RiskAllele=A
|Pval=0.000001
|OR=21.49
|ORtxt=[7.71-35.27] pg/mL decrease
|OA=1
}}

{{PharmGKB
|RSID=rs11254363
|Name_s=
|Gene_s=CUBN
|Feature=
|Evidence=PubMed ID:19303062; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations. (Initial Sample Size: 2,934 individuals; Replication Sample Size: 686 individuals); (Region: 10p13; Reported Gene(s): CUBN; Risk Allele: rs11254363-A); (p-value= 0.000001).This variant is associated with Folate pathway vitamins.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739919
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11254363
|overall_frequency_n=33
|overall_frequency_d=128
|overall_frequency=0.257812
|n_genomes=22
|n_genomes_annotated=0
|n_haplomes=28
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}