{{Rsnum
|rsid=1129456
|Gene=GREM1
|Chromosome=15
|position=32734466
|Orientation=plus
|GMAF=0.2075
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=GREM1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 76.6 | 23.4 | 0.0
| HCB | 57.8 | 40.0 | 2.2
| JPT | 66.7 | 28.9 | 4.4
| YRI | 42.9 | 39.7 | 17.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 57.8 | 40.0 | 2.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[[rs1129456]] is a SNP in the  gremlin 1 [[GREM1]] gene.

An analysis combining several populations (~1,300 patients) indicated that the [[rs1129456]](T) allele is associated with greater risk of nephropathy (odds ratio 1.69, CI: 1.36 - 2.11) among [[type-1 diabetes]] patients.{{PMID|20150533|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}