{{Rsnum
|rsid = 1135728
|Gene = TCF7
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Chromosome=5
|position=134143082
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=TCF7
}}(Trp336Cys) in the HMG_box region of this gene is predicted to be deleterious by many methods (SIFT, env_score, SDM and Polyphen) [http://www.biomedcentral.com/1471-2105/8/301]

{{PMID Auto
|PMID=17708757
|Title=Genome bioinformatic analysis of nonsynonymous SNPs.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}