{{Rsnum
|rsid=1143623
|Gene=IL1B
|Chromosome=2
|position=112838252
|Orientation=minus
|GMAF=0.2984
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=IL1B
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 12.7 | 41.3 | 46.0
| HCB | 13.6 | 50.0 | 36.4
| JPT | 13.3 | 40.0 | 46.7
| YRI | 0.0 | 11.3 | 88.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 13.6 | 50.0 | 36.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=18336824
|Title=Genetic variants within the interleukin-1 gene cluster, and risk of incident myocardial infarction, and ischemic stroke: a nested case-control approach
|OA=1
}}{{PMID|18838388}} Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis.

{{PMID|18936436|OA=1
}} Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994.

{{PMID|19478423|OA=1
}} Cytokine response to vitamin E supplementation is dependent on pre-supplementation cytokine levels.

{{PMID|19604093|OA=1
}} Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.

{{PMID|19934104|OA=1
}} Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.

{{PMID|21307135|OA=1
}} Interleukin 1B variant -1473G/C (rs1143623) influences triglyceride and interleukin 6 metabolism.

{{PMID|21649724}} Variation in human genetic polymorphisms, their association with Helicobacter pylori acquisition and gastric cancer in a multi-ethnic country.
{{PMID Auto
|PMID=24194923
|Title=Interactions between Diet, Lifestyle and IL10, IL1B, and PTGS2/COX-2 Gene Polymorphisms in Relation to Risk of Colorectal Cancer in a Prospective Danish Case-Cohort Study
|OA=1
}}
{{PMID Auto
|PMID=23927441
|Title=Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus
|OA=1
}}