{{Rsnum
|rsid=1148259
|Gene=ANKRD30A
|Chromosome=10
|position=37508450
|Orientation=minus
|ReferenceAllele=A
|GMAF=0.4867
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 14.2 | 45.1 | 40.7
| HCB | 47.4 | 43.8 | 8.8
| JPT | 55.8 | 38.1 | 6.2
| YRI | 12.9 | 45.6 | 41.5
| ASW | 23.2 | 41.1 | 35.7
| CHB | 47.4 | 43.8 | 8.8
| CHD | 38.5 | 48.6 | 12.8
| GIH | 50.5 | 42.6 | 6.9
| LWK | 14.5 | 47.3 | 38.2
| MEX | 22.4 | 53.4 | 24.1
| MKK | 17.9 | 51.3 | 30.8
| TSI | 20.6 | 50.0 | 29.4
| HapMapRevision=28
}}
[[rs1148259]] is a SNP located in the ankyrin repeat domain 30A [[ANKRD30A]] gene.

A study of metabolite concentrations in the blood of 284 adult males from Southern Germany determined that several SNPs were associated either directly with a metabolite range or with a ratio of metabolites. The rarer [[rs1148259]](T) allele was associated with increased sphingomyelin ratios. {{doi|10.1371/journal.pgen.1000282}}

[[Image:rs1148259_296x292.jpg|296px|thumb|left|]]

{{PMID Auto GWAS
|PMID=19043545
|Trait=Serum metabolites
|Title=Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
|RiskAllele=
|Pval=3E-9
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PharmGKB
|RSID=rs1148259
|Name_s=
|Gene_s=ANKRD30A
|Feature=
|Evidence=PubMed ID:19043545; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum. (Initial Sample Size: 284 males; Replication Sample Size: NR); (Region: 10p11.21; Reported Gene(s): ANKRD30A; Risk Allele: rs1148259-?); (p-value= 0.000000003).This variant is associated with Serum metabolites.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740314
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1148259
|overall_frequency_n=3932
|overall_frequency_d=9622
|overall_frequency=0.408647
|n_genomes=40
|n_genomes_annotated=0
|n_haplomes=55
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | Affy GenomeWide 6}}