{{Rsnum
|rsid=11523871
|Gene=DMBT1
|Chromosome=10
|position=124329710
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=A
|GMAF=0.3007
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 42.9 | 49.2 | 7.9
| HCB | 65.9 | 31.8 | 2.3
| JPT | 67.4 | 32.6 | 0.0
| YRI | 41.0 | 50.8 | 8.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 65.9 | 31.8 | 2.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs11523871]], also known as 124A>C or Thr42Pro, is a SNP in the Deleted in Malignant Brain Tumors 1 [[DMBT1]] gene.

For more information about increased [[breast cancer]] risk for this SNP, see the SNPedia entry for [[rs2981745]], to which it is tightly linked.{{PMID|19830809}} 

{{Venter SNP
|rsid=11523871
|allele=A
|frequency=
|uid=1103694078106
|type=homozygous_SNP
|hugo=DMBT1
|ensembl gene=ENSG00000187908
|ensembl transcript=ENST00000368915
|sift=
|disease=Inactivation of DMBT1 plays an important role in carcinogenesis. A loss or reduction of DMBT1 expression was seen in esophageal, gastric, lung and colorectal carcinomas. Deleted in medulloblastoma and glioblastoma cell lines. Homozygous deletions may be the predominant mechanism of inactivation.
}}

{{ neighbor
| rsid = 3013236
| distance = 717
}}

{{GET Evidence
|gene=DMBT1
|aa_change=Pro42Thr
|aa_change_short=P42T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11523871
|overall_frequency_n=6549
|overall_frequency_d=9688
|overall_frequency=0.675991
|n_genomes=50
|n_genomes_annotated=0
|n_haplomes=79
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.941
|nblosum100=4
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}