{{Rsnum
|rsid=1154404
|Gene=ADH5
|Chromosome=4
|position=99087853
|Orientation=minus
|GMAF=0.2612
|Gene_s=ADH5,SLC3A1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 25.0 | 41.1 | 33.9
| HCB | 0.0 | 8.3 | 91.7
| JPT | 0.0 | 17.9 | 82.1
| YRI | 0.0 | 9.3 | 90.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 8.3 | 91.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}linked to [[asthma]]

{{PMID|17543375|OA=1
}} Carrying 1 or 2 copies of the minor allele of SNP [[rs1154404]] was associated with decreased risk of asthma (relative risk [RR], 0.77; 95% CI, 0.61-0.97; P = .028 for 1 copy and RR, 0.66; 95% CI, 0.44-0.99; P = .046 for 2 copies). Homozygosity for the minor allele increased risk of asthma (RR, 1.60; 95% CI, 1.13-2.26; P = .0077). 

CLINICAL IMPLICATIONS: The association of GSNOR polymorphisms with asthma suggests a potential therapeutic target.

{{on chip | 23andMe v2}}