{{Rsnum
|rsid=11549467
|Gene=HIF1A
|Chromosome=14
|position=61740857
|Orientation=plus
|GMAF=0.01056
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=HIF1A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 1.8 | 98.2
| HCB | 0.0 | 6.7 | 93.3
| JPT | 0.0 | 6.2 | 93.8
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 6.7 | 93.3
| CHD | 0.0 | 10.1 | 89.9
| GIH | 0.0 | 1.0 | 99.0
| LWK | 0.0 | 0.9 | 99.1
| MEX | 0.0 | 1.8 | 98.2
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 2.0 | 98.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20412701
|Title=Lack of association between hypoxia inducible factor-1 alpha gene polymorphisms and biopsy-proven giant cell arteritis
}}

{{PMID Auto
|PMID=20572162
|Title=Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk
}}

{{PMID Auto
|PMID=22825513
|Title=Association of thymidylate synthase and hypoxia inducible factor-1alpha DNA polymorphisms with pancreatic cancer
}}

{{PMID Auto
|PMID=18980686
|Title=Non-synonymous sequence variants within the oxygen-dependent degradation domain of the HIF1A gene are not associated with pre-eclampsia in the Finnish population.
|OA=1
}}

{{PMID Auto
|PMID=19546348
|Title=Genetic variations in the hypoxia-inducible factor-1alpha gene and lung cancer.
}}

{{PMID Auto
|PMID=20389299
|Title=Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.
|OA=1
}}

{{PMID Auto
|PMID=20540786
|Title=The association of 18F-deoxyglucose (FDG) uptake of PET with polymorphisms in the glucose transporter gene (SLC2A1) and hypoxia-related genes (HIF1A, VEGFA, APEX1) in non-small cell lung cancer. SLC2A1 polymorphisms and FDG-PET in NSCLC patients.
|OA=1
}}

{{PMID Auto
|PMID=21778301
|Title=The polymorphisms in the VHL and HIF1A genes are associated with the prognosis but not the development of renal cell carcinoma.
}}

{{PMID Auto
|PMID=23042446
|Title=Genetic polymorphisms in HIF1A are associated with prostate cancer risk in a Chinese population
|OA=1
}}

{{GET Evidence
|gene=HIF1A
|aa_change=Ala588Thr
|aa_change_short=A588T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11549467
|overall_frequency_n=61
|overall_frequency_d=10758
|overall_frequency=0.0056702
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23631762
|Title=Genotyping analysis and 18FDG uptake in breast cancer patients: a preliminary research
|OA=1
}}

{{PMID Auto
|PMID=24050543
|Title=A polymorphism in the 3' untranslated region of Hypoxia-Inducible Factor-1 alpha confers an increased risk of cervical cancer in a Chinese population
}}

{{PMID Auto
|PMID=24195510
|Title=A polymorphism in the 3' untranslated region of Hypoxia-Inducible Factor-1 alpha confers an increased risk of cervical cancer in a Chinese population
}}

{{PMID Auto
|PMID=23583797
|Title=1790 G/A polymorphism, but not 1772 C/T polymorphism, is significantly associated with cancers: an update study.
}}

{{PMID Auto
|PMID=24824937
|Title=Update meta-analysis on 1790G/A polymorphism and cancer risk: Evidence from 26 studies
}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}