{{Rsnum
|rsid=11558471
|Gene=SLC30A8
|Chromosome=8
|position=117173494
|Orientation=plus
|GMAF=0.2874
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SLC30A8
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 54.0 | 41.6 | 4.4
| HCB | 28.7 | 47.8 | 23.5
| JPT | 28.3 | 50.4 | 21.2
| YRI | 88.4 | 10.9 | 0.7
| ASW | 66.7 | 31.6 | 1.8
| CHB | 28.7 | 47.8 | 23.5
| CHD | 26.6 | 53.2 | 20.2
| GIH | 63.4 | 29.7 | 6.9
| LWK | 90.0 | 10.0 | 0.0
| MEX | 60.3 | 34.5 | 5.2
| MKK | 91.0 | 8.3 | 0.6
| TSI | 53.9 | 39.2 | 6.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20081858
|Trait=Fasting glucose-related traits
|Title=New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
|RiskAllele=A
|Pval=3E-11
|OR=None
|ORtxt=None
|OA=1
}}

{{PharmGKB
|RSID=rs11558471
|Name_s=
|Gene_s=SLC30A8
|Feature=
|Evidence=PubMed ID:20081858
|Annotation=Phenotype: In a meta-analysis of 21 GWAS cohorts, this SNP was found to be associated with fasting glucose level. Study size: 45,996. Significance metric(s): p = 2.6 x 10(-11). Study population/ethnicity: Non-diabetic Individuals of European descent. Type of association: CO;GN.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus, Type 2
|Curation Level=Curated
|PharmGKB Accession ID=PA165281947
}}

{{PMID Auto
|PMID=21949744
|Title=Effects of 16 Genetic Variants on Fasting Glucose and Type 2 Diabetes in South Asians: ADCY5 and GLIS3 Variants May Predispose to Type 2 Diabetes
|OA=1
}}

{{PMID Auto GWAS
|PMID=21873549
|Trait=None
|Title=Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
|RiskAllele=A
|Pval=3E-18
|OR=None
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=20018041
|Title=The effect of multiple genetic variants in predicting the risk of type 2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=20550665
|Title=Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population.
|OA=1
}}

{{PMID Auto
|PMID=21810599
|Title=Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.
|OA=1
}}

{{PMID Auto GWAS
|PMID=22581228
|Trait=None
|Title=A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|RiskAllele=
|Pval=3E-20
|OR=None
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=22653633
|Title=SLC30A8 (ZnT8) variations and  type 2 diabetes in the Chinese Han population
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11558471
|overall_frequency_n=28
|overall_frequency_d=128
|overall_frequency=0.21875
|n_genomes=19
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23343670
|Title=Higher Magnesium Intake Is Associated with Lower Fasting Glucose and Insulin, with No Evidence of Interaction with Select Genetic Loci, in a Meta-Analysis of 15 CHARGE Consortium Studies
|OA=1
}}

{{PMID Auto
|PMID=22996130
|Title=From mice to humans.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}