{{Rsnum
|rsid=11564148
|Gene=LRRK2
|Chromosome=12
|position=40320099
|Orientation=plus
|GMAF=0.2755
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=LRRK2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 15.4 | 49.2 | 35.4
| HCB | 11.1 | 48.9 | 40.0
| JPT | 6.8 | 34.1 | 59.1
| YRI | 6.3 | 27.0 | 66.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.1 | 48.9 | 40.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{omim
|desc=LEUCINE-RICH REPEAT KINASE 2; LRRK2
|id=609007
|rsnum=11564148
}}

{{PMID Auto
|PMID=15726496
|Title=Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations.
|OA=1
}}

{{PMID Auto
|PMID=16960813
|Title=LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.
|OA=1
}}

{{PMID Auto
|PMID=18952485
|Title=Haplotype analysis of Lrrk2 R1441H carriers with parkinsonism.
|OA=1
}}

{{PMID Auto
|PMID=19343804
|Title=LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease.
|OA=1
}}

{{GET Evidence
|gene=LRRK2
|aa_change=Ser1647Thr
|aa_change_short=S1647T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11564148
|overall_frequency_n=2767
|overall_frequency_d=10742
|overall_frequency=0.257587
|n_genomes=16
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=1
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-2
|autoscore=3
|n_web_uneval=7
}}

{{ClinVar
|ALT=A
|CAF=0.7245; 0.2755
|CHROM=12
|CLNACC=RCV000032475.1
|CLNALLE=1
|CLNDBN=Parkinson disease 8, autosomal dominant
|CLNDSDB=GeneReviews:GeneReviews:MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1208:NBK1223:C1846862:607060:2828
|CLNHGVS=NC_000012.11:g.40713901T>A
|CLNSRC=GeneReviews
|CLNSRCID=NBK1208
|COMMON=1
|Disease=Parkinson disease 8
|FwdALT=A
|FwdREF=T
|GENEINFO=LRRK2:120892
|GENE_ID=120892
|GENE_NAME=LRRK2
|REF=T
|RSPOS=40713901
|Reversed=0
|SAO=0
|SSR=0
|Tags=PM;PMC;SLO;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|VC=SNV
|VP=0x05016800000015051f110101
|WGT=0
|dbSNPBuildID=120
|rsid=11564148
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}