{{Rsnum
|rsid=11597390
|Chromosome=10
|position=101861435
|Orientation=plus
|GMAF=0.2534
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.1 | 50.0 | 41.9
| HCB | 0.0 | 16.8 | 83.2
| JPT | 0.0 | 8.0 | 92.0
| YRI | 2.7 | 28.6 | 68.7
| ASW | 3.5 | 36.8 | 59.6
| CHB | 0.0 | 16.8 | 83.2
| CHD | 1.8 | 13.8 | 84.4
| GIH | 1.0 | 22.2 | 76.8
| LWK | 1.9 | 31.5 | 66.7
| MEX | 24.6 | 50.9 | 24.6
| MKK | 2.0 | 21.6 | 76.5
| TSI | 21.0 | 49.0 | 30.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18940312
|Trait=Plasma levels of liver enzymes
|Title=Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
|RiskAllele=A
|Pval=2E-8
|OR=0.04
|ORtxt=[0.025-0.053] U/L decrease
|OA=1
}}

{{omim
|desc=ALANINE AMINOTRANSFERASE, PLASMA LEVEL OF, QUANTITATIVE TRAIT LOCUS
|id=612363
|rsnum=11597390
}}

{{PharmGKB
|RSID=rs11597390
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18940312; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (Initial Sample Size: 7,751 European white individuals; Replication Sample Size: 4,704 European white and Indian Asian individua); (Region: 10q24.2q; Reported Gene(s): CPN1, CHUK, ERLIN1; Risk Allele: rs11597390-A); (p-value= 0.00000002).This variant is associated with Plasma levels of liver enzymes.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740803
}}

{{PMID Auto
|PMID=19822575
|Title=Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11597390
|overall_frequency_n=40
|overall_frequency_d=128
|overall_frequency=0.3125
|n_genomes=26
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}