{{Rsnum
|rsid=11668477
|Chromosome=19
|position=11084354
|Orientation=plus
|GMAF=0.2966
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 67.0 | 29.5 | 3.6
| HCB | 80.0 | 15.6 | 4.4
| JPT | 73.2 | 25.0 | 1.8
| YRI | 7.0 | 35.9 | 57.0
| ASW | 7.0 | 47.4 | 45.6
| CHB | 80.0 | 15.6 | 4.4
| CHD | 77.1 | 19.3 | 3.7
| GIH | 53.5 | 40.6 | 5.9
| LWK | 5.5 | 46.8 | 47.7
| MEX | 60.7 | 33.9 | 5.4
| MKK | 24.4 | 35.9 | 39.7
| TSI | 70.6 | 26.5 | 2.9
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19060910
|Trait=LDL cholesterol
|Title=Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
|RiskAllele=G
|Pval=2E-7
|OR=0.13
|ORtxt=[0.08-0.17] mmol/l decrease
|OA=1
}}

{{PharmGKB
|RSID=rs11668477
|Name_s=
|Gene_s=LDLR
|Feature=
|Evidence=PubMed ID:19060910; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. (Initial Sample Size: 4,763 individuals; Replication Sample Size: NR); (Region: 19p13.2; Reported Gene(s): LDLR; Risk Allele: rs11668477-G); (p-value= 0.0000002).This variant is associated with LDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740278
}}

{{PMID Auto
|PMID=17239995
|Title=Genetic study evaluating LDLR polymorphisms and Alzheimer's disease.
}}

{{PMID Auto
|PMID=18262040
|Title=LDL-cholesterol concentrations: a genome-wide association study.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11668477
|overall_frequency_n=49
|overall_frequency_d=122
|overall_frequency=0.401639
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=45
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}