{{Rsnum
|rsid=11701
|Gene=ANG
|Chromosome=14
|position=20693894
|Orientation=plus
|ReferenceAllele=T
|GMAF=0.1175
|Gene_s=ANG,RNASE4
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 1.8 | 24.8 | 73.5
| HCB | 0.7 | 2.9 | 96.4
| JPT | 0.0 | 5.3 | 94.7
| YRI | 0.7 | 21.1 | 78.2
| ASW | 3.5 | 22.8 | 73.7
| CHB | 0.7 | 2.9 | 96.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 25.7 | 74.3
| LWK | 3.6 | 33.6 | 62.7
| MEX | 0.0 | 34.5 | 65.5
| MKK | 9.6 | 34.0 | 56.4
| TSI | 2.9 | 24.5 | 72.5
| HapMapRevision=28
}}The common form at this site in most populations is [[rs11701]](T), and the variant form is [[rs11701]](G).

Having at least one copy of this variant form, [[rs11701]](G), has been associated with an increased incidence of [[ALS]] in Scottish and Irish populations studied, but not in populations from the U.S., Sweden, or England. {{PMID|16501576}}

*[[rs11701]] In Irish amyotrophic lateral sclerosis patients, there was a significant allelic association with the rs11701 SNP & a new mutation (K40I) that potentially inhibits angiogenin function.

{{omim
|desc=AMYOTROPHIC LATERAL SCLEROSIS 9; ALS9
|id=611895
|rsnum=11701
}}

{{omim
|desc=ANGIOGENIN; ANG
|id=105850
|rsnum=11701
}}

{{PMID Auto
|PMID=15557516
|Title=A novel candidate region for ALS on chromosome 14q11.2.
}}

{{PMID Auto
|PMID=17113198
|Title=Absence of angiogenic genes modification in Italian ALS patients.
}}

{{PMID Auto
|PMID=17462671
|Title=Variations in the coding and regulatory sequences of the angiogenin (ANG) gene are not associated to ALS (amyotrophic lateral sclerosis) in the Italian population.
}}

{{PMID Auto
|PMID=17703939
|Title=A novel Angiogenin gene mutation in a sporadic patient with amyotrophic lateral sclerosis from southern Italy.
}}

{{PMID Auto
|PMID=18852347
|Title=Mutations of the ANG gene in French patients with sporadic amyotrophic lateral sclerosis.
}}

{{PMID Auto
|PMID=19363631
|Title=Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis.
|OA=1
}}

{{PMID Auto
|PMID=22292798
|Title=Identification of a novel missense mutation in angiogenin in a Chinese amyotrophic lateral sclerosis cohort.
}}

{{PMID Auto
|PMID=25206666
|Title=Angiogenin gene polymorphism: A risk factor for diabetic peripheral neuropathy in the northern Chinese Han population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}