{{Rsnum
|rsid=1170191
|Gene=DGKH
|Chromosome=13
|position=42101357
|Orientation=minus
|GMAF=0.2681
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DGKH
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 73.5 | 23.9 | 2.7
| HCB | 30.7 | 48.9 | 20.4
| JPT | 21.2 | 52.2 | 26.5
| YRI | 83.7 | 15.0 | 1.4
| ASW | 64.9 | 35.1 | 0.0
| CHB | 30.7 | 48.9 | 20.4
| CHD | 30.6 | 50.0 | 19.4
| GIH | 54.5 | 37.6 | 7.9
| LWK | 76.4 | 23.6 | 0.0
| MEX | 48.3 | 43.1 | 8.6
| MKK | 75.6 | 23.7 | 0.6
| TSI | 65.7 | 29.4 | 4.9
| HapMapRevision=28
}}In a survey that scanned 80 genes, no SNPs with a large effect were found to be associated with [[bipolar disorder]]. However, the SNP with the largest association was [[rs1170191]], in first intron of the diacylglycerol kinase eta [[DGKH]] gene. The odds ratio for the risk allele of this SNP is 1.59 (p = 1.5x10e-8, experiment-wide p<0.01).{{PMID|17486107|OA=1
}}

{{PMID Auto
|PMID=18421293
|Title=Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement.
|OA=1
}}

{{PMID Auto
|PMID=19308021
|Title=Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
|OA=1
}}

{{PMID Auto
|PMID=19818381
|Title=Interacting genes in lithium prophylaxis: preliminary results of an exploratory analysis on the role of DGKH and NR1D1 gene polymorphisms in 199 Sardinian bipolar patients.
}}

{{PMID Auto
|PMID=22048461
|Title=Effect of variation in diacylglycerol kinase eta (DGKH) gene on brain function in a cohort at familial risk of bipolar disorder.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}