{{Rsnum
|rsid=11706052
|Gene=IMPDH2
|Chromosome=3
|position=49026677
|Orientation=plus
|GMAF=0.07254
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IMPDH2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 77.0 | 23.0 | 0.0
| HCB | 89.8 | 10.2 | 0.0
| JPT | 85.0 | 15.0 | 0.0
| YRI | 0.0 | 0.0 | 0.0
| ASW | 96.5 | 3.5 | 0.0
| CHB | 89.8 | 10.2 | 0.0
| CHD | 89.9 | 10.1 | 0.0
| GIH | 94.1 | 5.9 | 0.0
| LWK | 97.3 | 2.7 | 0.0
| MEX | 87.9 | 12.1 | 0.0
| MKK | 89.7 | 10.3 | 0.0
| TSI | 79.4 | 18.6 | 2.0
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19770842
|Title=An inosine 5'-monophosphate dehydrogenase 2 single-nucleotide polymorphism impairs the effect of mycophenolic acid
}}

{{PharmGKB
|RSID=rs11706052
|Name_s=IMPDH2:IVS7+10T>C
|Gene_s=DALRD3, IMPDH2
|Feature=NA, Intron
|Evidence=PubMed ID:19770842
|Annotation=Lymphocytes carrying the C allele of the IMPDH2:IVS7+10T>C variant had less of a response to mycophenolic acid treatment compared to cells from TT individuals.
|Drugs=mycophenolic acid
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165107204
}}

{{PMID Auto
|PMID=20679962
|Title=Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil
|OA=1
}}

{{PMID Auto
|PMID=21996196
|Title=Lymphocyte Counts in Kidney Allograft Recipients Are Associated With IMPDH2 3757T&gt;C Gene Polymorphism
}}

{{PMID Auto
|PMID=21955043
|Title=Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort
|OA=1
}}

{{PMID Auto
|PMID=19617864
|Title=Interpatient variability in IMPDH activity in MMF-treated renal transplant patients is correlated with IMPDH type II 3757T > C polymorphism.
}}

{{PMID Auto
|PMID=20061166
|Title=Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11706052
|overall_frequency_n=836
|overall_frequency_d=10758
|overall_frequency=0.0777096
|n_genomes=10
|n_genomes_annotated=0
|n_haplomes=10
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=22960765
|Title=Inosine monophosphate dehydrogenase polymorphisms and renal allograft outcome.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}