{{Rsnum
|rsid=1176744
|Gene=HTR3B
|Chromosome=11
|position=113932306
|Orientation=minus
|GMAF=0.343
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=HTR3B
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 8.8 | 40.7 | 50.4
| HCB | 1.5 | 24.3 | 74.3
| JPT | 8.0 | 41.1 | 50.9
| YRI | 20.0 | 48.3 | 31.7
| ASW | 12.3 | 45.6 | 42.1
| CHB | 1.5 | 24.3 | 74.3
| CHD | 2.8 | 21.3 | 75.9
| GIH | 22.8 | 38.6 | 38.6
| LWK | 40.2 | 43.9 | 15.9
| MEX | 17.9 | 30.4 | 51.8
| MKK | 33.3 | 49.4 | 17.3
| TSI | 7.9 | 41.6 | 50.5
| HapMapRevision=28
}}

{{omim
|desc=5-@HYDROXYTRYPTAMINE RECEPTOR 3B; HTR3B
|id=604654
|rsnum=1176744
}}

{{PMID Auto
|PMID=19741568
|Title=Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders
}}

{{PMID Auto
|PMID=20838391
|Title=Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence
|OA=1
}}

{{PMID Auto
|PMID=21570824
|Title=Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids
}}

{{PMID|17708757|OA=1
}} Genome bioinformatic analysis of nonsynonymous SNPs.

{{PMID|18330705|OA=1
}} Physiogenomic analysis of localized FMRI brain activity in schizophrenia.

{{PMID|19185213|OA=1
}} HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power--an intermediate phenotype for alcoholism and co-morbid behaviors.

{{PMID|21172166|OA=1
}} Pharmacogenetics of antidepressant response.

{{PMID|21184810}} Are serotonin 3A and 3B receptor genes associated with suicidal behavior in schizophrenia subjects?

{{GET Evidence
|gene=HTR3B
|aa_change=Tyr129Ser
|aa_change_short=Y129S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1176744
|overall_frequency_n=3841
|overall_frequency_d=10756
|overall_frequency=0.357103
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=47
|n_articles=0
|n_articles_annotated=0
|nblosum100=5
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23757001
|Title=Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence
}}

{{PMID Auto
|PMID=23290502
|Title=Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}