{{Rsnum
|rsid=11803731
|Gene=TCHH
|Chromosome=1
|position=152110849
|Orientation=plus
|GMAF=0.1006
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=TCHH
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 57.8 | 34.4 | 7.8
| HCB | 97.7 | 2.3 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 97.7 | 2.3 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[[rs11803731]], a SNP in the Trichohyalin gene ([[TCHH]]) gene, is estimated to account for 6% of the variance in hair morphology (ie [[hair curliness]]) based on a study of Australians of European ancestry.{{PMID|19896111|OA=1
}}

{{PMID Auto GWAS
|PMID=19896111
|Trait=Hair morphology
|Title=Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans
|RiskAllele=A
|Pval=3E-31
|OR=6.11
|ORtxt=[NR] % variance
|OA=1
}}

{{omim
|id=139450
|rsnum=11803731
}}

{{PMID Auto
|PMID=20585627
|Title=Web-based, participant-driven studies yield novel genetic associations for common traits.
|OA=1
}}

{{GET Evidence
|gene=TCHH
|aa_change=Leu790Met
|aa_change_short=L790M
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11803731
|overall_frequency_n=1344
|overall_frequency_d=10140
|overall_frequency=0.132544
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|nblosum100=-3
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}