{{Rsnum
|rsid=11805303
|Gene=IL23R
|Chromosome=1
|position=67209833
|Orientation=plus
|GMAF=0.3333
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL23R
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 51.3 | 38.9 | 9.7
| HCB | 22.6 | 52.6 | 24.8
| JPT | 16.8 | 53.1 | 30.1
| YRI | 42.9 | 46.9 | 10.2
| ASW | 49.1 | 49.1 | 1.8
| CHB | 22.6 | 52.6 | 24.8
| CHD | 16.5 | 55.0 | 28.4
| GIH | 18.0 | 50.0 | 32.0
| LWK | 56.4 | 35.5 | 8.2
| MEX | 65.5 | 32.8 | 1.7
| MKK | 47.4 | 44.2 | 8.3
| TSI | 37.6 | 54.5 | 7.9
| HapMapRevision=28
}}
[[rs11805303]] has been reported in a large study to be associated with [[Crohn's disease]].

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.39 (CI 1.22-1.58), and for homozygotes, 1.86 (CI 1.54-2.24). {{PMID|17554300|OA=1
}}

{{omim
|desc=INFLAMMATORY BOWEL DISEASE 17; IBD17
|id=612261
|rsnum=11805303
}}

{{omim
|desc=INTERLEUKIN 23 RECEPTOR; IL23R
|id=607562
|rsnum=11805303
}}

{{PMID Auto
|PMID=18438406
|Title=Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|OA=1
}}

{{PMID Auto
|PMID=18533027
|Title=Worldwide population differentiation at disease-associated SNPs.
|OA=1
}}

{{PMID Auto
|PMID=19249008
|Title=Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.
|OA=1
}}

{{PMID Auto
|PMID=19522770
|Title=Variants of the IL23R gene are associated with ankylosing spondylitis but not with Sjogren syndrome in Hungarian population samples.
}}

{{PMID Auto
|PMID=19757086
|Title=Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients.
}}

{{PMID Auto
|PMID=19918037
|Title=Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis.
|OA=1
}}

{{PMID Auto
|PMID=20978829
|Title=Polymorphisms of the IL23R gene are associated with psoriasis but not with immunoglobulin A nephropathy in a Hungarian population.
}}

{{PMID Auto
|PMID=22426692
|Title=Confirmation of three inflammatory bowel disease susceptibility loci in a Chinese cohort.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs11805303
|overall_frequency_n=40
|overall_frequency_d=128
|overall_frequency=0.3125
|n_genomes=27
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23093364
|Title=Difference of interleukin-23 receptor gene haplotype variants in ulcerative colitis compared to Crohn's disease and psoriasis
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}