{{Rsnum
|rsid=1183910
|Gene=HNF1A
|Chromosome=12
|position=120983004
|Orientation=minus
|GMAF=0.3039
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=HNF1A
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 50.8 | 43.1 | 6.2
| HCB | 28.9 | 53.3 | 17.8
| JPT | 13.6 | 52.3 | 34.1
| YRI | 85.7 | 11.1 | 3.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 28.9 | 53.3 | 17.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[http://blog.23andme.com/2009/06/30/genetic-study-casts-doubt-on-inflammatory-marker-as-cause-of-heart-disease/ 23andMe blog] each rs1183910(T) lowered CRP by 13.8% also associated with higher total cholesterol, LDL choesterol and HDL cholesterol.
{{PMID Auto
|PMID=19567438
|Title=Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease
|OA=1
}}

{{PMID Auto GWAS
|PMID=21300955
|Trait=None
|Title=Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
|RiskAllele=G
|Pval=2E-124
|OR=0.1490
|ORtxt=[0.14-0.16] unit increase
|OA=1
}}

{{PMID Auto
|PMID=18439552
|Title=Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs1183910
|overall_frequency_n=32
|overall_frequency_d=128
|overall_frequency=0.25
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=28
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23844046
  |Trait=C-reactive protein
  |Title=Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
  |RiskAllele=G
  |Pval=4E-12
  |OR=.05
  |ORtxt=[NR] unit increase
  |OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}