{{Rsnum
|rsid=11889341
|Gene=STAT4
|Chromosome=2
|position=191079016
|Orientation=plus
|GMAF=0.2456
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=STAT4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 67.7 | 26.2 | 6.2
| HCB | 40.0 | 51.1 | 8.9
| JPT | 62.2 | 26.7 | 11.1
| YRI | 74.2 | 21.0 | 4.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 40.0 | 51.1 | 8.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{omim
|desc=RHEUMATOID ARTHRITIS; RA
|id=180300
|rsnum=11889341
}}

{{omim
|id=600558
|desc=SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 4; STAT4
|rsnum=11889341
}}

{{PMID Auto
|PMID=19737838
|Title=A haplotype in STAT4 gene associated with rheumatoid arthritis in Caucasians is not associated in the Han Chinese population, but with the presence of rheumatoid factor
}}
{{PMID Auto
|PMID=19950257
|Title=Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: Evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines
|OA=1
}}

{{PMID Auto
|PMID=20176035
|Title=Association of signal transducer and activator of transcription 4 genetic variants with extra-intestinal manifestations in inflammatory bowel disease
}}

{{PMID Auto
|PMID=21683716
|Title=Signal transducer and activator of transcription 4 gene polymorphisms associated with rheumatoid arthritis in Northwestern Chinese Han population
}}

{{PMID Auto
|PMID=22483685
|Title=Interactions between IL17A, IL23R, and STAT4 polymorphisms confer susceptibility to intestinal Behcet's disease in Korean population
}}

{{PMID|17932559|OA=1
}} Association of STAT4 with rheumatoid arthritis in the Korean population.

{{PMID|18434327|OA=1
}} Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility.

{{PMID|18516230|OA=1
}} Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

{{PMID|18579578|OA=1
}} A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

{{PMID|18803832|OA=1
}} Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.

{{PMID|19674979|OA=1
}} Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

{{PMID|20454450|OA=1
}} Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.

{{PMID|22569826}} Abnormal Genetic and Epigenetic Changes in Signal Transducer and Activator of Transcription 4 in the Pathogenesis of Inflammatory Bowel Diseases.

{{PMID Auto
|PMID=24059108
|Title=[Signal transducer and activator of transcription 4 gene polymorphisms associated with dilated cardiomyopathy in Chinese Han population]
}}

{{PMID Auto
|PMID=24386384
|Title=Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis
|OA=1
}}

{{PMID Auto GWAS
  |PMID=24390342
  |Trait=Rheumatoid arthritis
  |Title=Genetics of rheumatoid arthritis contributes to biology and drug discovery.
  |RiskAllele=T
  |Pval=4E-19
  |OR=1.13
  |ORtxt=[1.10-1.17]
  }}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}