{{Rsnum
|rsid=12007229
|Chromosome=X
|position=67528513
|Orientation=plus
|GMAF=0.101
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 4.4 | 13.3 | 82.3
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 16.3 | 19.0 | 64.6
| ASW | 8.9 | 10.7 | 80.4
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 4.0 | 2.0 | 94.1
| LWK | 20.9 | 21.8 | 57.3
| MEX | 1.7 | 5.2 | 93.1
| MKK | 16.0 | 17.9 | 66.0
| TSI | 6.9 | 6.9 | 86.3
| HapMapRevision=28
}}[[rs12007229]] is located on the X chromosome near the androgen receptor gene.

In a genome-wide association study of 5700 dementia-free individuals, 67 patients developed incident vascular [[dementia]] over a mean follow-up time of 9.3±3.2 years. The [[rs12007229]](A) allele was associated with this development (odds ratio 3.7, CI: 2.3-5.8, p = 1.3×10e-8). The association was further confirmed in 2 independent populations (probability value of combined replication samples=0.024).{{PMID|22116812}}

{{PMID Auto
|PMID=15570555
|Title=Systematic evaluation of genetic variation at the androgen receptor locus and risk of prostate cancer in a multiethnic cohort study.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}