{{Rsnum
|rsid=120074192
|Chromosome=11
|Orientation=plus
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=KCNQ1
|position=2527959
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=KCNQ1
}}{{omim
|id=607542
|rsnum=120074192
|variant=0032
}}{{ClinVar
|rsid=120074192
|Reversed=0
|FwdREF=A
|FwdALT=G
|REF=A
|ALT=G
|RSPOS=2549189
|CHROM=11
|dbSNPBuildID=132
|SSR=0
|SAO=1
|VP=0x050168000000000002110100
|GENEINFO=KCNQ1:3784
|GENE_NAME=KCNQ1
|GENE_ID=3784
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000011.9:g.2549189A>G
|CLNSRC=OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=607542.0032
|CLNSIG=5
|CLNCUI=C1837014
|CLNDBN=Atrial fibrillation, familial, 3; not provided
|Disease=Atrial fibrillation; not provided
|CLNACC=RCV000003293.1; RCV000057673.1
|Tags=PM;PMC;SLO;OTHERKG;LSD;OM
|CLNDSDB=MedGen:OMIM
|CLNDSDBID=C1837014:607554
}}{{PMID|12522251}} KCNQ1 gain-of-function mutation in familial atrial fibrillation.

{{PMID|15368194|OA=1
}} Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation.

{{PMID|17467630}} Human KCNQ1 S140G mutation is associated with atrioventricular blocks.

{{PMID|18599533|OA=1
}} Mechanisms by which atrial fibrillation-associated mutations in the S1 domain of KCNQ1 slow deactivation of IKs channels.

{{PMID|21224508}} The S140G KCNQ1 atrial fibrillation mutation affects 'I(KS)' profile during both atrial and ventricular action potentials.