{{Rsnum
|rsid=12025416
|Gene=LOC100506459
|Chromosome=1
|position=116495665
|Orientation=plus
|GMAF=0.4458
|Gene_s=HMGB1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 3.2 | 29.0 | 67.7
| HCB | 48.9 | 42.2 | 8.9
| JPT | 54.5 | 36.4 | 9.1
| YRI | 58.7 | 36.5 | 4.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 48.9 | 42.2 | 8.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=21244703
|Trait=None
|Title=Modeling the Cumulative Genetic Risk for Multiple Sclerosis from Genome Wide Association Data
|RiskAllele=
|Pval=1E-7
|OR=1.4500
|ORtxt=[1.25-1.69]
|OA=1
}}{{PMID Auto
|PMID=19525953
|Title=Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
|OA=1
}}