{{Rsnum
|rsid=12029454
|Gene=NOS1AP
|Chromosome=1
|position=162163327
|Orientation=plus
|GMAF=0.2511
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=NOS1AP
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 27.4 | 71.7
| HCB | 10.2 | 41.6 | 48.2
| JPT | 15.0 | 43.4 | 41.6
| YRI | 10.9 | 33.3 | 55.8
| ASW | 12.3 | 42.1 | 45.6
| CHB | 10.2 | 41.6 | 48.2
| CHD | 9.2 | 49.5 | 41.3
| GIH | 15.8 | 49.5 | 34.7
| LWK | 5.5 | 34.5 | 60.0
| MEX | 3.4 | 25.9 | 70.7
| MKK | 3.8 | 31.4 | 64.7
| TSI | 3.0 | 31.7 | 65.3
| HapMapRevision=28
}}[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PMID Auto GWAS
|PMID=19305408
|Trait=QT interval
|Title=Common variants at ten loci influence QT interval duation in the QTGEN Study
|RiskAllele=A
|Pval=3E-45
|OA=1
}}

{{PharmGKB
|RSID=rs12029454
|Name_s=
|Gene_s=NOS1AP
|Feature=
|Evidence=PubMed ID:19305408; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci influence QT interval duation in the QTGEN Study. (Initial Sample Size: 13,685 individuals; Replication Sample Size: 15,854 individuals); (Region: 1q23.3; Reported Gene(s): NOS1AP; Risk Allele: rs12029454-A); (p-value= 3E-45).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739886
}}

{{PMID Auto
|PMID=20722683
|Title=A common variant of NOS1AP is associated with QT interval duration in a Chinese population with Type 2 diabetes
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12029454
|overall_frequency_n=24
|overall_frequency_d=126
|overall_frequency=0.190476
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}