{{Rsnum
|rsid=12053903
|Gene=SCN5A
|Chromosome=3
|position=38551902
|Orientation=plus
|GMAF=0.4559
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SCN5A
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 9.7 | 40.7 | 49.6
| HCB | 28.5 | 53.3 | 18.2
| JPT | 24.8 | 54.9 | 20.4
| YRI | 81.6 | 17.7 | 0.7
| ASW | 57.9 | 36.8 | 5.3
| CHB | 28.5 | 53.3 | 18.2
| CHD | 31.5 | 45.4 | 23.1
| GIH | 11.9 | 33.7 | 54.5
| LWK | 75.5 | 23.6 | 0.9
| MEX | 22.4 | 60.3 | 17.2
| MKK | 62.8 | 34.0 | 3.2
| TSI | 10.8 | 49.0 | 40.2
| HapMapRevision=28
}}[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PMID Auto GWAS
|PMID=19305408
|Trait=QT interval
|Title=Common variants at ten loci influence QT interval duation in the QTGEN Study
|RiskAllele=C
|Pval=1E-14
|OR=1.23
|ORtxt=[0.88-1.57] msec decrease
|OA=1
}}

{{PharmGKB
|RSID=rs12053903
|Name_s=
|Gene_s=SCN5A
|Feature=
|Evidence=PubMed ID:19305408; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci influence QT interval duation in the QTGEN Study. (Initial Sample Size: 13,685 individuals; Replication Sample Size: 15,854 individuals); (Region: 3p22.2; Reported Gene(s): SCN5A; Risk Allele: rs12053903-C); (p-value= 0.00000000000001).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739893
}}

{{PMID Auto GWAS
|PMID=20062063
|Trait=Electrocardiographic traits
|Title=Several common variants modulate heart rate, PR interval and QRS duration
|RiskAllele=T
|Pval=1E-7
|OR=6.59
|ORtxt=[4.16-9.03] % SD decrease
}}

{{PMID Auto
|PMID=20062060
|Title=Genome-wide association study of PR interval.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12053903
|overall_frequency_n=66
|overall_frequency_d=128
|overall_frequency=0.515625
|n_genomes=40
|n_genomes_annotated=0
|n_haplomes=59
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}