{{Rsnum
|rsid=12188950
|Gene=PDE4D
|Chromosome=5
|position=60487490
|Orientation=plus
|GMAF=0.09229
|Gene_s=PDE4D
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}In both a multi-site study including 2,500+ Swedish patients and a meta-analysis of 10,000+ patients in 17 publications, no association between [[rs12188950]] and risk for ischemic stroke was found.
{{PMID|22274584|OA=1
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 70.8 | 27.4 | 1.8
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 84.1 | 14.5 | 1.4
| ASW | 86.0 | 14.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 98.2 | 1.8 | 0.0
| GIH | 90.1 | 9.9 | 0.0
| LWK | 81.8 | 16.4 | 1.8
| MEX | 89.7 | 10.3 | 0.0
| MKK | 92.3 | 7.7 | 0.0
| TSI | 62.7 | 32.4 | 4.9
| HapMapRevision=28
}}

{{PMID Auto
|PMID=16835261
|Title=Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.
|OA=1
}}

{{PMID Auto
|PMID=18398440
|Title=Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.
}}

{{PMID Auto
|PMID=19409523
|Title=Multilocus Bayesian meta-analysis of gene-disease associations.
|OA=1
}}

{{PMID Auto
|PMID=19426955
|Title=Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
|OA=1
}}

{{PMID Auto
|PMID=20540798
|Title=Sex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}