{{Rsnum
|rsid=121908153
|Chromosome=1
|Orientation=plus
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene=NLRP3
|position=247424356
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=NLRP3
}}{{omim
|id=606416
|rsnum=121908153
|variant=0008
}}
{{omim
|id=120100
|rsnum=121908153
}}{{ClinVar
|rsid=121908153
|Reversed=0
|FwdREF=G
|FwdALT=A,C
|REF=G
|ALT=A,C
|RSPOS=247587658
|CHROM=1
|dbSNPBuildID=132
|SSR=0
|SAO=1
|VP=0x050168000000000002110100
|GENEINFO=NLRP3:114548
|GENE_NAME=NLRP3
|GENE_ID=114548
|WGT=0
|VC=SNV
|CLNALLE=1; 2
|CLNHGVS=NC_000001.10:g.247587658G>A; NC_000001.10:g.247587658G>C
|CLNORIGIN=1
|CLNSRCID=
606416.0008; 112; 581
|CLNSIG=5
|CLNCUI=
|CLNACC=
RCV000004626.1; RCV000004627.1; RCV000084240.1; RCV000084241.1
|Tags=PM;PMC;SLO;OTHERKG;LSD;OM
|CLNDBN=Chronic infantile neurological, cutaneous and articular syndrome; Familial amyloid nephropathy with urticaria AND deafness; Familial cold urticaria
|CLNDSDB=MedGen:OMIM:Orphanet:SNOMED_CT
|CLNDSDBID=C0409818:607115:1451:239826001; C0268390:191900:575:15123008; C0343068:120100:47045:238687000
|CLNSRC=OMIM Allelic Variant; UnitÃ© mÃ©dicale des maladies autoinflammatoires
|Disease=Chronic infantile neurological; Familial amyloid nephropathy with urticaria AND deafness; Familial cold urticaria
}}{{PMID Auto
|PMID=11992256
|Title=New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes.
|OA=1
}}