{{Rsnum
|rsid=121912713
|Chromosome=14
|Orientation=minus
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene=SERPINA1
|position=94378561
|Gene_s=SERPINA1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}{{omim
|id=107400
|rsnum=121912713
|variant=0026
}}{{ClinVar
|rsid=121912713
|Reversed=1
|FwdREF=T
|FwdALT=G
|REF=A
|ALT=C
|RSPOS=94844898
|CHROM=14
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050268000000000002110100
|GENEINFO=SERPINA1:5265
|GENE_NAME=SERPINA1
|GENE_ID=5265
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000014.8:g.94844898A>C
|CLNORIGIN=0
|CLNSIG=255
|Tags=RV;PM;PMC;S3D;OTHERKG;LSD;OM
|CLNACC=RCV000019591.1; RCV000019592.26
|CLNDBN=PI PITTSBURGH; 'antithrombin' pittsburgh
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=107400.0026
|Disease=PI PITTSBURGH; 'antithrombin' pittsburgh
}}{{PMID Auto
|PMID=1569192
|Title=Met 358 to Arg mutation of alpha 1-antitrypsin associated with protein C deficiency in a patient with mild bleeding tendency.
|OA=1
}}

{{PMID Auto
|PMID=3484756
|Title=Recombinant alpha 1-antitrypsin Pittsburgh (Met 358----Arg) is a potent inhibitor of plasma kallikrein and activated factor XII fragment.
|OA=1
}}

{{PMID Auto
|PMID=6604220
|Title=Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder.
}}

{{PMID Auto
|PMID=8182727
|Title=The molecular basis of genetic dominance.
|OA=1
}}