{{Rsnum
|rsid=121912762
|Chromosome=1
|Orientation=plus
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene=RHD
|position=25284753
|Gene_s=RHD
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}[[rs121912762]], also known as Leu110Pro, represents an important SNP in the rhesus factor [[RHD]] gene. 

As reported in several publications, such as {{PMID|7741145}}, the [[rs121912762]](C) allele leads to a lack of epD8 and the expression of the low frequency antigen Rh40. The result of this a rare Rh-positive variant known as D(VII). RHD D(VII) individuals will be typed as Rh+, yet they can develop anti-D antibodies following immunization by pregnancy or transfusion.

See also: [http://omim.org/entry/111680#0002 OMIM 111680.0002]
{{omim
|id=111680
|rsnum=121912762
|variant=0002
}}{{ClinVar
|rsid=121912762
|Reversed=0
|FwdREF=T
|FwdALT=C
|REF=T
|ALT=C
|RSPOS=25284753
|CHROM=1
|dbSNPBuildID=133
|SSR=0
|SAO=1
|VP=0x050260400a05040002110100
|GENEINFO=RHD:6007
|GENE_NAME=RHD
|GENE_ID=6007
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.25284753T>C
|CLNORIGIN=1
|CLNSIG=5
|Tags=PM;S3D;NSM;REF;U5;ASP;VLD;OTHERKG;LSD;OM
|CLNACC=RCV000019286.22
|CLNDBN=Rhd category d-vii
|CLNSRC=ClinVar; OMIM Allelic Variant
|CLNSRCID=NM_001282867.1:c.-166T>C; NM_016124.4:c.329T>C; 111680.0002
|Disease=Rhd category d-vii
}}