{{Rsnum
|rsid=12225230
|Gene=SIK3
|Chromosome=11
|position=116857914
|Orientation=plus
|GMAF=0.1501
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=SIK3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 3.1 | 24.6 | 72.3
| HCB | 0.0 | 17.8 | 82.2
| JPT | 0.0 | 15.6 | 84.4
| YRI | 1.6 | 17.5 | 81.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 17.8 | 82.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs12225230
|Name_s=
|Gene_s=KIAA0999
|Feature=
|Evidence=PubMed ID:19802338
|Annotation=Phenotype: In a GWAS, this SNP was significantly associated with plasma concentrations of apolipoprotein A1. Study size: 6382. Study population/ethnicity: Caucasian women. Significance metric(s): ApoA1: p = 4.0 x 10(-9). Type of association: CO; GN
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA165111813
}}

{{PMID Auto
|PMID=19041386
|Title=Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|OA=1
}}

{{GET Evidence
|gene=SIK3
|aa_change=Pro1078Arg
|aa_change_short=P1078R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12225230
|overall_frequency_n=1721
|overall_frequency_d=10758
|overall_frequency=0.159974
|n_genomes=12
|n_genomes_annotated=0
|n_haplomes=13
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.877
|nblosum100=5
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}