{{Rsnum
|rsid=12251307
|Chromosome=10
|position=6123495
|Orientation=plus
|GMAF=0.1919
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 81.4 | 16.8 | 1.8
| HCB | 65.7 | 30.7 | 3.6
| JPT | 66.1 | 31.2 | 2.7
| YRI | 38.1 | 44.2 | 17.7
| ASW | 45.6 | 45.6 | 8.8
| CHB | 65.7 | 30.7 | 3.6
| CHD | 67.0 | 26.6 | 6.4
| GIH | 64.6 | 30.3 | 5.1
| LWK | 45.0 | 47.7 | 7.3
| MEX | 70.2 | 28.1 | 1.8
| MKK | 53.2 | 41.0 | 5.8
| TSI | 85.3 | 13.7 | 1.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18978792
|Trait=Type 1 diabetes
|Title=Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
|RiskAllele=T
|Pval=0.000002
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PMID Auto GWAS
|PMID=19430480
|Trait=Type 1 diabetes
|Title=Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
|RiskAllele=
|Pval=1E-13
|OR=NR
|ORtxt=NR
|OA=1
}}

{{PharmGKB
|RSID=rs12251307
|Name_s=
|Gene_s=RBM17
|Feature=
|Evidence=PubMed ID:18978792; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. (Initial Sample Size: 3,561 cases, 4,646 controls; Replication Sample Size: 6,225 cases, 6,946 controls, 3,064 trios); (Region: 10p15.1; Reported Gene(s): IL2RA; Risk Allele: rs12251307-T); (p-value= 0.000002).This variant is associated with Type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740757
}}

{{PMID Auto
|PMID=19956099
|Title=The type I diabetes association of the IL2RA locus
|OA=1
}}

{{PMID|17554260|OA=1
}} Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

{{PMID|19265545|OA=1
}} Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

{{PMID|19468064|OA=1
}} Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

{{PMID|19956101|OA=1
}} Overview of the Rapid Response data.

{{PMID|19956106|OA=1
}} Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12251307
|overall_frequency_n=21
|overall_frequency_d=128
|overall_frequency=0.164062
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}