{{Rsnum
|rsid=12257526
|Gene=GRID1
|Chromosome=10
|position=87928843
|Orientation=plus
|GMAF=0.1965
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 1.8 | 19.5 | 78.8
| HCB | 0.7 | 22.6 | 76.6
| JPT | 2.7 | 20.4 | 77.0
| YRI | 16.3 | 54.4 | 29.3
| ASW | 7.0 | 45.6 | 47.4
| CHB | 0.7 | 22.6 | 76.6
| CHD | 0.0 | 21.1 | 78.9
| GIH | 11.9 | 45.5 | 42.6
| LWK | 20.0 | 50.0 | 30.0
| MEX | 1.8 | 28.1 | 70.2
| MKK | 5.8 | 44.9 | 49.4
| TSI | 4.0 | 21.8 | 74.3
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs12257526
|Name_s=
|Gene_s=GRID1
|Feature=
|Evidence=PubMed ID:17537913
|Annotation=Risk or phenotype-associated allele: not stated Phenotype: Using a Quantitative Transmission Disequilibrium Test (QTDT), this variant was significantly associated with etoposide toxicity based upon IC50 values in cell lines from 30 parent-child trios. Study size: 87. Study population/ethnicity: 87 European descent Caucasians. Significance metric(s): p = 0.00002. Type of association: FA; GN.
|Drugs=etoposide
|Drug Classes=
|Diseases=Drug Toxicity
|Curation Level=Curated
|PharmGKB Accession ID=PA165109408
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12257526
|overall_frequency_n=27
|overall_frequency_d=128
|overall_frequency=0.210938
|n_genomes=23
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}