{{Rsnum
|rsid=12289128
|Gene=LOC100288077
|Chromosome=11
|position=102809235
|Orientation=plus
|GMAF=0.06336
|Gene_s=COX6CP3
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 0.0 | 15.0 | 85.0
| HCB | 0.0 | 1.5 | 98.5
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 21.8 | 78.2
| ASW | 0.0 | 29.8 | 70.2
| CHB | 0.0 | 1.5 | 98.5
| CHD | 0.0 | 0.9 | 99.1
| GIH | 0.0 | 20.8 | 79.2
| LWK | 0.0 | 24.8 | 75.2
| MEX | 0.0 | 5.2 | 94.8
| MKK | 1.3 | 23.7 | 75.0
| TSI | 1.0 | 23.5 | 75.5
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs12289128
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:20031604
|Annotation=In a GWAS performed on 778 healthy Amish adults, the G allele of rs12289128 was associated with higher levels of circulating MMP1. Risk or phenotype-associated allele: G allele. Phenotype: associated with higher circulating MMP1 levels. Study size:778. Study population/ethnicity: healthy Amish adults. Significance metric(s): P value: p less than or equal to 10(-7). Type of association: CO; GN.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA165111638
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12289128
|overall_frequency_n=9
|overall_frequency_d=128
|overall_frequency=0.0703125
|n_genomes=7
|n_genomes_annotated=0
|n_haplomes=7
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=9
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}