{{Rsnum
|rsid=12338
|Gene=CTSB
|Chromosome=8
|position=11853379
|Orientation=minus
|GMAF=0.4054
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=CTSB
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 41.0 | 55.7 | 3.3
| HCB | 19.0 | 57.1 | 23.8
| JPT | 24.4 | 48.8 | 26.8
| YRI | 38.7 | 46.8 | 14.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 19.0 | 57.1 | 23.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{omim
|desc=TROPICAL CALCIFIC PANCREATITIS
|id=608189
|rsnum=12338
}}

{{omim
|desc=CATHEPSIN B; CTSB
|id=116810
|rsnum=12338
}}

{{GET Evidence
|gene=CTSB
|aa_change=Leu26Val
|aa_change_short=L26V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12338
|overall_frequency_n=3915
|overall_frequency_d=10758
|overall_frequency=0.363915
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=35
|n_articles=0
|n_articles_annotated=0
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=22851129
|Title=Cathepsin B SNPs elevate the pathological development of oral cancer and raise the susceptibility to carcinogen-mediated oral cancer.
}}

{{PMID Auto
|PMID=25106406
|Title=A4383C and C76G SNP in Cathepsin B is respectively associated with the high risk and tumor size of hepatocarcinoma
}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}