{{Rsnum
|rsid=12469063
|Gene=MEIS1
|Chromosome=2
|position=66537176
|Orientation=plus
|GMAF=0.1928
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=MEIS1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 57.5 | 38.9 | 3.5
| HCB | 55.9 | 40.4 | 3.7
| JPT | 54.9 | 42.5 | 2.7
| YRI | 100.0 | 0.0 | 0.0
| ASW | 89.5 | 10.5 | 0.0
| CHB | 55.9 | 40.4 | 3.7
| CHD | 51.9 | 39.8 | 8.3
| GIH | 45.5 | 46.5 | 7.9
| LWK | 98.2 | 1.8 | 0.0
| MEX | 56.9 | 36.2 | 6.9
| MKK | 88.5 | 11.5 | 0.0
| TSI | 47.1 | 49.0 | 3.9
| HapMapRevision=28
}}[[rs12469063]], a SNP located in the [[MEIS1]] gene, has been linked to [[restless legs syndrome]], a common sleep disorder, with an overall odds ratio of 1.78 (CI: 1.52-2.10) for the (G) risk allele. {{PMID|17637780}}

The association from this region that gives the highest association to [[restless legs syndrome]], however, is a haplotype consisting of the [[rs6710341]](A) and [[rs12469063]](G) alleles. This haplotype gives rise to an odds ratio of 2.75 (CI: 2.23-3.41). {{PMID|17637780}}

{{PMID Auto
|PMID=19223043
|Title=Exploring the genetic link between RLS and [[ADHD]]
}}

{{omim
|id=612853
|rsnum=12469063
}}

{{PMID|19126776|OA=1
}} MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels.

{{PMID|19279021|OA=1
}} Replication of restless legs syndrome loci in three European populations.

{{PMID|20396431|OA=1
}} Genotyping sleep disorders patients.

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}