{{Rsnum
|rsid=12537284
|Chromosome=7
|position=129077852
|Orientation=plus
|GMAF=0.06474
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 23.0 | 75.2
| HCB | 0.0 | 0.7 | 99.3
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.7 | 99.3
| ASW | 0.0 | 5.3 | 94.7
| CHB | 0.0 | 0.7 | 99.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 4.0 | 24.8 | 71.3
| LWK | 0.0 | 3.6 | 96.4
| MEX | 3.4 | 24.1 | 72.4
| MKK | 0.0 | 14.7 | 85.3
| TSI | 2.9 | 15.7 | 81.4
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18204446
|Trait=Systemic lupus erythematosus in women
|Title=Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
|RiskAllele=A
|Pval=3.9999999999999999E-19
|OR=1.54
|ORtxt=[1.40-1.70]
|OA=1
}}

{{PMID Auto
|PMID=22440820
|Title=IRF5 polymorphism predicts prognosis in patients with systemic sclerosis
|OA=1
}}

{{PMID Auto
|PMID=18853133
|Title=Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.
|OA=1
}}

{{PMID Auto
|PMID=20383147
|Title=Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.
|OA=1
}}

{{PMID Auto
|PMID=21408207
|Title=Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12537284
|overall_frequency_n=7
|overall_frequency_d=128
|overall_frequency=0.0546875
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}