{{Rsnum
|rsid=12614
|Gene=CFB
|Chromosome=6
|position=31946402
|Orientation=plus
|GMAF=0.1671
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CFB
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 81.2 | 17.0 | 1.8
| HCB | 84.7 | 14.6 | 0.7
| JPT | 82.0 | 15.3 | 2.7
| YRI | 38.8 | 44.2 | 17.0
| ASW | 46.4 | 37.5 | 16.1
| CHB | 84.7 | 14.6 | 0.7
| CHD | 90.8 | 8.3 | 0.9
| GIH | 72.0 | 23.0 | 5.0
| LWK | 42.2 | 48.6 | 9.2
| MEX | 81.0 | 19.0 | 0.0
| MKK | 32.3 | 59.4 | 8.4
| TSI | 71.6 | 27.5 | 1.0
| HapMapRevision=28
}}{{omim
|id=138470
|rsnum=12614
|variant=0002
}}

{{PMID Auto
|PMID=21541267
|Title=Complement factor B polymorphism 32W protects against age-related macular degeneration
|OA=1
}}

{{ClinVar
|rsid=12614
|Reversed=0
|FwdREF=C
|FwdALT=T
|REF=C
|ALT=T
|RSPOS=31914179
|CHROM=6
|GMAF=0.1671
|dbSNPBuildID=52
|SSR=0
|SAO=1
|VP=0x05036800000015051f110100
|GENEINFO=CFB:629
|GENE_NAME=CFB
|GENE_ID=629
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000006.11:g.31914179C>T
|CLNORIGIN=1
|CLNSIG=2
|Tags=PM;PMC;S3D;SLO;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.8329; 0.1671
|CLNACC=RCV000017455.1
|CLNDBN=Factor B fast/slow polymorphism
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=138470.0002
|COMMON=1
|Disease=Factor B fast/slow polymorphism
}}

{{PMID Auto
|PMID=19696172
|Title=The involvement of complement factor B and complement component C2 in an Indian cohort with age-related macular degeneration.
}}

{{GET Evidence
|gene=CFB
|aa_change=Arg32Trp
|aa_change_short=R32W
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12614
|overall_frequency_n=20
|overall_frequency_d=128
|overall_frequency=0.15625
|n_genomes=14
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.854
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=7
|autoscore=4
|n_web_uneval=6
}}

{{PMID Auto
|PMID=23919682
|Title=Complement alternative pathway genetic variation and Dengue infection in the Thai population
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}