{{Rsnum
|rsid=12619285
|Chromosome=2
|position=212959321
|Orientation=plus
|GMAF=0.4059
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 57.5 | 36.3 | 6.2
| HCB | 15.3 | 45.3 | 39.4
| JPT | 8.0 | 48.7 | 43.4
| YRI | 43.2 | 37.7 | 19.2
| ASW | 52.6 | 35.1 | 12.3
| CHB | 15.3 | 45.3 | 39.4
| CHD | 17.4 | 40.4 | 42.2
| GIH | 60.4 | 36.6 | 3.0
| LWK | 33.6 | 54.5 | 11.8
| MEX | 31.6 | 38.6 | 29.8
| MKK | 38.5 | 45.5 | 16.0
| TSI | 55.9 | 36.3 | 7.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19198610
|Trait=Plasma eosinophil count
|Title=Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
|RiskAllele=G
|Pval=5E-10
|OR=6.30
|ORtxt=[4.3-8.3] % standard unit increase
}}

{{PharmGKB
|RSID=rs12619285
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198610; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. (Initial Sample Size: 9,392 individuals; Replication Sample Size: 12,118 individuals); (Region: 2q34; Reported Gene(s): IKZF2; Risk Allele: rs12619285-G); (p-value= 0.0000000005).This variant is associated with Plasma eosinophil count.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739959
}}

{{PMID Auto
|PMID=19860791
|Title=Genetic evidence for a role of IL33 in nasal polyposis.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12619285
|overall_frequency_n=50
|overall_frequency_d=128
|overall_frequency=0.390625
|n_genomes=32
|n_genomes_annotated=0
|n_haplomes=41
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=23328882
|Title=Meta-analyses of four eosinophil related gene variants in coronary heart disease.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}