{{Rsnum
|rsid=12621278
|Gene=ITGA6
|Chromosome=2
|position=172446825
|Orientation=plus
|GMAF=0.08953
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ITGA6
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 92.0 | 8.0 | 0.0
| HCB | 50.4 | 43.0 | 6.7
| JPT | 63.7 | 31.0 | 5.3
| YRI | 100.0 | 0.0 | 0.0
| ASW | 98.2 | 1.8 | 0.0
| CHB | 50.4 | 43.0 | 6.7
| CHD | 56.9 | 37.6 | 5.5
| GIH | 78.2 | 20.8 | 1.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 94.6 | 5.4 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 96.0 | 4.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19767753
|Trait=Prostate cancer
|Title=Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
|RiskAllele=G
|Pval=9E-23
|OR=1.33
|ORtxt=[1.25-1.43]
|OA=1
}}

{{PMID Auto
|PMID=20651075
|Title=Prostate Cancer Susceptibility Variants Confer Increased Risk of Disease Progression
|OA=1
}}

According to a 23andMe report, the [[rs12621278(A;A)]] genotype is associated with 2.4 times higher risk of progression of [[prostate cancer]]. {{PMID|20651075|OA=1
}}

{{PMID Auto
|PMID=21820706
|Title=Prostate Cancer Risk Alleles and Their Associations With Other Malignancies
|OA=1
}}

{{PMID Auto
|PMID=21390317
|Title=Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12621278
|overall_frequency_n=8
|overall_frequency_d=128
|overall_frequency=0.0625
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=8
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=2
|webscore=N
|n_web_uneval=8
}}

{{PMID Auto
|PMID=23405784
|Title=[Susceptibility to prostate cancer in Han Chinese: single nucleotide polymorphism analysis of 1 667 cases]
}}

{{PMID Auto
|PMID=23620269
|Title=Genetic variants in 2q31 and 5p15 are associated with aggressive benign prostatic hyperplasia in a Chinese population.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}