{{Rsnum
|rsid=12670798
|Gene=DNAH11
|Chromosome=7
|position=21567734
|Orientation=plus
|GMAF=0.3081
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DNAH11
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 2.7 | 33.6 | 63.7
| HCB | 25.5 | 41.6 | 32.8
| JPT | 23.9 | 47.8 | 28.3
| YRI | 11.7 | 40.7 | 47.6
| ASW | 10.5 | 54.4 | 35.1
| CHB | 25.5 | 41.6 | 32.8
| CHD | 26.9 | 40.7 | 32.4
| GIH | 3.0 | 30.7 | 66.3
| LWK | 16.4 | 34.5 | 49.1
| MEX | 1.7 | 44.8 | 53.4
| MKK | 7.7 | 44.2 | 48.1
| TSI | 0.0 | 43.1 | 56.9
| HapMapRevision=28
}}per the [http://blog.23andme.com/2008/12/08/new-papers-from-nature-genetics-yield-a-bounty-of-cholesterol-snps/ 23andMe blog], the minor allele of this SNP (C) was associated with increased [[cholesterol]] and [[triglycerides]]
 
{| border="1"
|-
!SNP
!Rarer allele
!LDL
!HDL
!TG
|-
| [[rs6544713]] || T || + || ||
|-
| [[rs2650000]] || A || + || ||
|-
| [[rs471364]] || C || || - ||
|-
| [[rs1800961]] || T || || - ||
|-
| [[rs7679]] || C || || - || +
|-
| [[rs2967605]] || T || || - ||
|-
| [[rs2409722]] || T || || || -
|-
| [[rs10903129]] || A || - || - || -
|-
| [[rs6756629]] || A || - || + || -
|-
| [[rs12670798]] || C || + || + || +
|-
| [[rs7395662]] || A || - || + || +
|-
| [[rs174570]] || T || - || - || +
|-
| [[rs2271293]] || A || - || + || -
|-
| [[rs2624265]] || C || || || +
|-
| [[rs2167079]] || T || || + ||
|-
| [[rs9891572]] || T || || + ||
|-
| [[rs4844614]] || T || + || ||
|-
| [[rs5031002]] || G || + || ||
|-
|}

{{PMID Auto GWAS
|PMID=19060911
|Trait=Cholesterol, total
|Title=Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
|RiskAllele=G
|Pval=9E-7
|OR=0.06
|ORtxt=[NR] SD increase
|OA=1
}}

{{PharmGKB
|RSID=rs12670798
|Name_s=
|Gene_s=DNAH11
|Feature=
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 17,797 individuals; Replication Sample Size: NR); (Region: 7p15.3; Reported Gene(s): DNAH11; Risk Allele: rs12670798-G); (p-value= 0.000000006).This variant is associated with LDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740224
}}

{{PharmGKB
|RSID=rs12670798
|Name_s=
|Gene_s=DNAH11
|Feature=
|Evidence=PubMed ID:19060911; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. (Initial Sample Size: 22,562 individuals; Replication Sample Size: NR); (Region: 7p15.3; Reported Gene(s): DNAH11; Risk Allele: rs12670798-G); (p-value= 0.0000009).This variant is associated with Cholesterol, total.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740193
}}

{{PMID Auto GWAS
|PMID=20686565
|Trait=None
|Title=Biological, clinical and population relevance of 95 loci for blood lipids.
|RiskAllele=T
|Pval=7E-10
|OR=1.7000
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=19951432
|Title=Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
|OA=1
}}

{{PMID Auto
|PMID=20502693
|Title=Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs12670798
|overall_frequency_n=35
|overall_frequency_d=128
|overall_frequency=0.273438
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=33
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}