{{Rsnum
|rsid = 12688128
|Gene = IL1RAPL2
|geno1 = (A;A)
|geno2 = (A;T)
|geno3 = (T;T)
|Orientation=plus
|Chromosome=X
|position=104747771
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=IL1RAPL2
}}influences the risk of thyrotoxic hypokalaemic periodic paralysis

{{PMID|17970773}} [[rs750841]] (A > T) in intron 3 of the gamma-aminobutyric acid (GABA) receptor alpha3 subunit (GABRA3) gene possessed the most significant difference in allele frequency (27% in THPP case and 5% in controls, P = 0.007). Actual allele frequencies obtained from genotyping in each individual were very similar to the estimated frequency from the pools (28% in THPP and 2% in controls, and P = 0.0002). Nearby DNA sequences of GABRA3 were sequenced and an additional two SNPs were found (A > C at exon 1 and G > T of [[rs12688128]]). Allele A of [[rs750841]] and allele G of rs12688128 in intron 3 were predominantly found in THPP with significant genetic relative risk of 19 (P < 0.0002; 95%CI 2.4-151.6).

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}