{{Rsnum
|rsid=12721646
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Chromosome=19
|Orientation=plus
|Gene=CYP2A
|position=41009202
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=CYP2B6
}}{{PharmGKB
|RSID=rs12721646
|Name_s=c.646-17C>T
|Gene_s=CYP2B7P1, CYP2A7P1
|Feature=
|Evidence=PubMed ID:20017669
|Annotation=Risk or phenotype-associated allele: T. Phenotype: This variant is statistically correlated with the mean of maximum transaminase values (ALT) in patients from Mozambique, with higher ALT mean value for T genotype carriers. Study size: 156. Study population/ethnicity: HIV infected patients from Mozambique. Significance metric(s): p= 0.007. Type of association: GN; CO
|Drugs=nevirapine
|Drug Classes=
|Diseases=Drug Toxicity; HIV Infections
|Curation Level=Curated
|PharmGKB Accession ID=PA165111623
}}